Mouse Upstream stimulatory factor 1 ELISA Kit | Usf1 elisa kit
Mouse Upstream stimulatory factor 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013]
Uniprot Description
USF1: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 1q22-q23
Cellular Component: nucleoplasm; nucleus; transcription factor complex
Molecular Function: bHLH transcription factor binding; enzyme binding; histone deacetylase binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding
Biological Process: cellular response to insulin stimulus; glucose homeostasis; late viral mRNA transcription; lipid homeostasis; negative regulation of fibrinolysis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by glucose; regulation of transcription by carbon catabolites; regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter by glucose; response to hypoxia; response to UV; transcription from RNA polymerase II promoter
Disease: Hyperlipidemia, Combined, 1
Research Articles on Usf1
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Product Notes
The Mouse Usf1 usf1 (Catalog #AAA2887986) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887986 ELISA Kit recognizes Mouse Usf1. It is sometimes possible for the material contained within the vial of "Upstream stimulatory factor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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