Human unc-5 homolog A (C. elegans) ELISA Kit | UNC5A elisa kit
Human Netrin receptor UNC5A, UNC5A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]
Uniprot Description
UNC5A: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Belongs to the unc-5 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell development/differentiation; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q35.2
Cellular Component: plasma membrane; integral to membrane
Biological Process: axon guidance; positive regulation of apoptosis; anterior/posterior axon guidance
Research Articles on UNC5A
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Product Notes
The Human UNC5A unc5a (Catalog #AAA9327800) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327800 ELISA Kit recognizes Human UNC5A. It is sometimes possible for the material contained within the vial of "unc-5 homolog A (C. elegans), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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