55 kDa immediate-early protein 1 (UL123) Recombinant Protein | UL123 recombinant protein
Recombinant Human cytomegalovirus 55 kDa immediate-early protein 1 (UL123)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
55 kDa immediate-early protein 1 (UL123); Recombinant Human cytomegalovirus 55 kDa immediate-early protein 1 (UL123); UL123 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-491, Full length protein
Sequence
MESSAKRKMDPDNPDEGPSSKVPRPETPVTKATTFLQTMLRKEVNSQLSLGDPLFPELAEESLKTFERVTEDCNENPEKDVLAELVKQIKVRVDMVRHRIKEHMLKKYTQTEEKFTGAFNMMGGCLQNALDILDKVHEPFEEMKCIGLTMQSMYENYIVPEDKREMWMACIKELHDVSKGAANKLGGALQAKARAKKDELRRKMMYMCYRNIEFFTKNSAFPKTTNGCSQAMAALQNLPQCSPDEIMAYAQKIFKILDEERDKVLTHIDHIFMDILTTCVETMCNEYKVTSDACMMTMYGGISLLSEFCRVLSCYVLEETSVMLAKRPLITKPEVISVMKRRIEEICMKVFAQYILGADPLRVCSPSVDDLRAIAEESDEEEAIVAYTLATRGASSSDSLVSPPESPVPATIPLSSVIVAENSDQEESEQSDEEEEEGAQEEREDTVSVKSEPVSEIEEVAPEEEEDGAEEPTASGGKSTHPMVTRSKADQ
Sequence Length
491
Species
Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
55,179 Da
NCBI Official Full Name
55 kDa immediate-early protein 1
UniProt Protein Name
55 kDa immediate-early protein 1
Protein Family
UniProt Gene Name
UL123
UniProt Synonym Gene Names
IE1
Uniprot Description
Plays an important role in transactivating viral early genes as well as activating its own promoter. Targets and disrupts host PML/nuclear domain 10 (ND10). Promotes efficient viral growth by interacting with and directing host SP100 to degradation, leading to enhanced acetylation level of histones. In addition, functions in counteracting the host innate antiviral response. Inhibits the type I interferon pathway by directly interacting with and sequestrating host STAT2. Alters host cell cycle progression, probably through its interaction with host E2F1 or RB1 that overcomes the RB1-mediated repression of E2F-responsive promoters.
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Product Notes
The UL123 ul123 (Catalog #AAA1091082) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-491, Full length protein. The amino acid sequence is listed below: MESSAKRKMD PDNPDEGPSS KVPRPETPVT KATTFLQTML RKEVNSQLSL GDPLFPELAE ESLKTFERVT EDCNENPEKD VLAELVKQIK VRVDMVRHRI KEHMLKKYTQ TEEKFTGAFN MMGGCLQNAL DILDKVHEPF EEMKCIGLTM QSMYENYIVP EDKREMWMAC IKELHDVSKG AANKLGGALQ AKARAKKDEL RRKMMYMCYR NIEFFTKNSA FPKTTNGCSQ AMAALQNLPQ CSPDEIMAYA QKIFKILDEE RDKVLTHIDH IFMDILTTCV ETMCNEYKVT SDACMMTMYG GISLLSEFCR VLSCYVLEET SVMLAKRPLI TKPEVISVMK RRIEEICMKV FAQYILGADP LRVCSPSVDD LRAIAEESDE EEAIVAYTLA TRGASSSDSL VSPPESPVPA TIPLSSVIVA ENSDQEESEQ SDEEEEEGAQ EEREDTVSVK SEPVSEIEEV APEEEEDGAE EPTASGGKST HPMVTRSKAD Q. It is sometimes possible for the material contained within the vial of "55 kDa immediate-early protein 1 (UL123), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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