Human U2AF homology motif (UHM) kinase 1 ELISA Kit | UHMK1 elisa kit

Human Serine/threonine-protein kinase Kist, UHMK1 ELISA Kit

Cat. Num. AAA9333900

• Gene Names: UHMK1; KIS; KIST; P-CIP2
• Reactivity: Human
• Synonyms: U2AF homology motif (UHM) kinase 1; Human Serine/threonine-protein kinase Kist; UHMK1 ELISA Kit; Human Serine/threonine-protein kinase Kist (UHMK1) ELISA kit; KIS; KIST; KIS protein kinase; U2AF homology motif kinase 1; kinase interacting stathmin; kinase interacting with leukemia-associated gene (stathmin) ; serine/threonine-protein kinase Kist; UHMK1 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 296179412
• NCBI GeneID: 127933
• NCBI Accession #: NP_001171692.1
• NCBI GenBank Nucleotide #: NM_001184763.1
• UniProt Accession #: Q8TAS1; Q96C22; A8K8K4; G3V1M1
• Molecular Weight: 46,546 Da
• NCBI Official Full Name: serine/threonine-protein kinase Kist isoform 2
• NCBI Official Synonym Full Names: U2AF homology motif (UHM) kinase 1
• NCBI Official Symbol: UHMK1
• NCBI Official Synonym Symbols: KIS; KIST; P-CIP2
• NCBI Protein Information: serine/threonine-protein kinase Kist; KIS protein kinase; PAM COOH-terminal interactor protein 2; kinase interacting with leukemia-associated gene (stathmin)
• UniProt Protein Name: Serine/threonine-protein kinase Kist
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: UHMK1
• UniProt Synonym Gene Names: KIS; KIST; P-CIP2
• UniProt Entry Name: UHMK1_HUMAN

NCBI Description

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

KIS: a unique kinase that possesses an RNP type RNA-recognition motif (RRM). A proline-directed kinase with a specificity different from the MAP kinases and CDKs. May be involved in trafficking and/or processing of RNA.

Protein type: Protein kinase, Other; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Other group; Other-Unique family

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: dendrite cytoplasm; axon; nucleus

Molecular Function: transferase activity; ribonucleoprotein binding; protein serine/threonine kinase activity; protein binding; enzyme binding; RNA binding; ATP binding

Biological Process: positive regulation of translational initiation; peptidyl-serine phosphorylation; protein amino acid autophosphorylation; cell cycle arrest; neurite development; regulation of protein export from nucleus