UDP-glucuronosyltransferase 2A1 (Ugt2a1) Recombinant Protein | Ugt2a1 recombinant protein
Recombinant Rat UDP-glucuronosyltransferase 2A1 (Ugt2a1)
NCBI and Uniprot Product Information
NCBI Description
enzyme important for the elimination of potentially toxic compounds; found in the olfactory epithelium and may be involved with olfaction [RGD, Feb 2006]
Uniprot Description
UGT2A1/2: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium. Belongs to the UDP-glycosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.4.1.17; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - ascorbate and aldarate; Membrane protein, integral; Transferase; Lipid Metabolism - androgen and estrogen
Cellular Component: intracellular membrane-bound organelle; integral to membrane
Molecular Function: transferase activity, transferring hexosyl groups; glucuronosyltransferase activity
Biological Process: flavonoid biosynthetic process; metabolic process; response to toxin; sensory perception of smell; cellular response to hormone stimulus
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Product Notes
The Ugt2a1 ugt2a1 (Catalog #AAA953627) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-490. The amino acid sequence is listed below: GNVLIWPMEG SHWLNVKIII DELLRKEHNV TVLVASGALF ITPSVSPSLT FEIYPVPFGK EKIESVIKDF VLTWLENRPS PSTIWTFYKE MAKVIEEFHL VSRGICDGVL KNEKLMTKLQ RGKFEVLLSD PVFPCGDIVA LKLGIPFIYS LRFSPASTVE KHCGKVPFPP SYVPAILSEL TDQMSFADRV RNFISYRMQD YMFETLWKQW DSYYSKALGR PTTLCETMGK AEIWLMRTYW DFEFPRPYLP NFEFVGGLHC KPAKPLPKEM EEFVQTSGEH GVVVFSLGSM VKNLTEEKAN LIASALAQIP QKVLWRYKGK IPATLGSNTR LFDWIPQNDL LGHPKTRAFI THGGTNGIYE AIYHGIPMVG VPMFADQPDN IAHMKAKGAA VEVNMNTMTS ADLLSAVRAV INEPFYKENA MRLSRIHHDQ PVKPLDRAVF WIEFVMRHKG AKHLRVAAHD LSWFQYHSLD. It is sometimes possible for the material contained within the vial of "UDP-glucuronosyltransferase 2A1 (Ugt2a1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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