NCBI and Uniprot Product Information
Uniprot Description
UBQLN1: Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors. Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 9q22|9q21.2-q21.3
Cellular Component: autophagic vacuole; cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; nucleoplasm; perinuclear region of cytoplasm; plasma membrane; proteasome complex; protein complex
Molecular Function: identical protein binding; kinase binding; polyubiquitin binding; protein binding
Biological Process: ER-associated protein catabolic process; negative regulation of toll-like receptor 3 signaling pathway; positive regulation of protein ubiquitination; regulation of macroautophagy; regulation of protein ubiquitination
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Product Notes
The Human UBQLN1 ubqln1 (Catalog #AAA2887327) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887327 ELISA Kit recognizes Human UBQLN1. It is sometimes possible for the material contained within the vial of "Ubiquilin-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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