Mouse ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) ELISA Kit | UBE2M elisa kit
Mouse NEDD8-conjugating enzyme Ubc12, UBE2M ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
UBE2M: Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. Interacts with UBA3, DCUN1D1 and RBX1. Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein type: EC 6.3.2.-; Ligase; EC 6.3.2.19; Ubiquitin conjugating system; Adaptor/scaffold; Ubiquitin ligase
Cellular Component: cytoplasm
Molecular Function: coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; ribosomal S6-glutamic acid ligase activity; nucleotide binding; ubiquitin-protein ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ATP binding; NEDD8 ligase activity; ligase activity
Biological Process: protein neddylation; positive regulation of neuron apoptosis; protein modification process; protein ubiquitination
Research Articles on UBE2M
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Product Notes
The Mouse UBE2M ube2m (Catalog #AAA9337028) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337028 ELISA Kit recognizes Mouse UBE2M. It is sometimes possible for the material contained within the vial of "ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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