U2-ctenitoxin-Cs1a Recombinant Protein | U1-CNTX-Cs2a recombinant protein
Recombinant Cupiennius salei U2-ctenitoxin-Cs1a
NCBI and Uniprot Product Information
Uniprot Description
Function: This toxin alone has very weak insecticidal activity, with an unknown molecular target. Acts as a neurotoxic enhancer, synergistically enhancing the neurotoxic action of omega-CNTX-Cs1a (CSTX-1) (AC P81694). Ref.1 Ref.2
Subunit structure: Heterodimer of A and B chains; disulfide-linked. Ref.1
Subcellular location: Secreted Ref.1.
Tissue specificity: Expressed by the venom gland. Ref.1
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin
By similarity.
Toxic dose: LD50 in Drosophila is 16.3 nmol/g. Ref.1
Sequence similarities: Belongs to the spider toxin CSTX superfamily.
Caution: It is probable that CSTX-13 A and B chains originate from the same gene. Both chains may be separated by some amino acids.
Mass spectrometry: Molecular mass is 4342.73 Da from positions 1 - 34. Determined by ESI. Ref.1Molecular mass is 3475.80 Da from positions 35 - 63. Determined by ESI. Ref.1
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Product Notes
The U2-ctenitoxin-Cs1a u1-cntx-cs2a (Catalog #AAA1185627) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-34aa; Cytoplasmic domain. The amino acid sequence is listed below: SDCTLRNHDC TDDRHSCCRS KMFKDVCTCF YPSQ. It is sometimes possible for the material contained within the vial of "U2-ctenitoxin-Cs1a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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