Human thioredoxin domain containing 12 (endoplasmic reticulum) ELISA Kit | TXNDC12 elisa kit

Human Thioredoxin domain-containing protein 12, TXNDC12 ELISA Kit

Cat. Num. AAA9337654

• Gene Names: TXNDC12; AG1; AGR1; ERP16; ERP18; ERP19; TLP19; hAG-1; PDIA16; hTLP19
• Reactivity: Human
• Synonyms: thioredoxin domain containing 12 (endoplasmic reticulum); Human Thioredoxin domain-containing protein 12; TXNDC12 ELISA Kit; Human Thioredoxin domain-containing protein 12 (TXNDC12) ELISA kit; AG1; AGR1; ERP18; ERP19; PDIA16; TLP19; hAG-1; anterior gradient homolog 1; endoplasmic reticulum thioredoxin superfamily member; 18 kDa; protein disulfide isomerase family A; member 16; thioredoxin do; TXNDC12 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for TXNDC12 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of TXNDC12 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 7705696
• NCBI GeneID: 51060
• NCBI Accession #: NP_056997.1
• NCBI GenBank Nucleotide #: NM_015913.3
• UniProt Accession #: O95881; Q5T1T4; Q96H50; B3KQS0
• Molecular Weight: 19,206 Da
• NCBI Official Full Name: thioredoxin domain-containing protein 12
• NCBI Official Synonym Full Names: thioredoxin domain containing 12 (endoplasmic reticulum)
• NCBI Official Symbol: TXNDC12
• NCBI Official Synonym Symbols: AG1; AGR1; ERP16; ERP18; ERP19; TLP19; hAG-1; PDIA16; hTLP19
• NCBI Protein Information: thioredoxin domain-containing protein 12; ER protein 18; ER protein 19; anterior gradient homolog 1; thioredoxin-like protein p19; endoplasmic reticulum protein ERp19; endoplasmic reticulum resident protein 18; endoplasmic reticulum resident protein 19; protein disulfide isomerase family A, member 16; endoplasmic reticulum thioredoxin superfamily member, 18 kDa
• UniProt Protein Name: Thioredoxin domain-containing protein 12
• Protein Family: Thioredoxin domain-containing protein
• UniProt Gene Name: TXNDC12
• UniProt Synonym Gene Names: TLP19; UNQ713/PRO1376; ER protein 18; ERp18; ER protein 19; ERp19
• UniProt Entry Name: TXD12_HUMAN

NCBI Description

This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]

Uniprot Description

TXNDC12: Possesses significant protein thiol-disulfide oxidase activity.

Protein type: Oxidoreductase; Secreted; Secreted, signal peptide; Other Amino Acids Metabolism - glutathione; EC 1.8.4.2

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: endoplasmic reticulum lumen

Molecular Function: protein-disulfide reductase (glutathione) activity

Biological Process: cell redox homeostasis