Thiosulfate sulfurtransferase (TST) Recombinant Protein | TST recombinant protein

Recombinant Human Thiosulfate sulfurtransferase (TST)

Cat. Num. AAA1433586

• Gene Names: TST; RDS
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Thiosulfate sulfurtransferase (TST); Recombinant Human Thiosulfate sulfurtransferase (TST); TST recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-297, Full length protein
• Sequence: VHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
• Sequence Length: 296

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for TST recombinant protein

The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin.

NCBI and Uniprot Product Information

• NCBI GI #: 395394071
• NCBI GeneID: 7263
• NCBI Accession #: NP_001257412.1
• NCBI GenBank Nucleotide #: NM_001270483.1
• UniProt Accession #: Q16762; Q6IB06; B3KRM1
• Molecular Weight: 33,429 Da
• NCBI Official Full Name: thiosulfate sulfurtransferase
• NCBI Official Synonym Full Names: thiosulfate sulfurtransferase
• NCBI Official Symbol: TST
• NCBI Official Synonym Symbols: RDS
• NCBI Protein Information: thiosulfate sulfurtransferase
• UniProt Protein Name: Thiosulfate sulfurtransferase
• Protein Family: Toxic shock syndrome toxin
• UniProt Gene Name: TST

NCBI Description

This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.