Thyrotropin receptor (TSHR) Recombinant Protein | TSHR recombinant protein
Recombinant Sheep Thyrotropin receptor (TSHR)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Thyrotropin receptor (TSHR); Recombinant Sheep Thyrotropin receptor (TSHR); Recombinant Thyrotropin receptor (TSHR); Thyrotropin receptor; Thyroid-stimulating hormone receptor; TSH-R; TSHR recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
22-413aa; Fragment at the N-terminal, provide the extracellular domain.
Sequence
ERCPSPPCECRQEDDFRVTCKDIQRIPSLPPSTQTLKFIETHLKTIPSRAFSNLPNISRIYLSIDATLQQLESHSFYNLSKVTHIEIRNTRSLTYIDSGALKELPLLKFLGIFNTGLRVFPDLTKIYSTDVFFILEITDNPYMTSVPANAFQGLSNETLTLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLTVIDQDAFAGVYSGPTLLDISYTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKNIRGILQSLMCNESSIWGLRQRKSASALNGPFYQEYEEDLGDGSAGYKENSKFQDTHSNSHYYVFFEDQEDEIIGFGQELKNPQEETLQAFDNHYDYTVCGGSEEMVCTPKSDEFNPCEDIMG
Species
Ovis aries (Sheep)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,674 Da
NCBI Official Full Name
thyrotropin receptor
NCBI Official Symbol
TSHR
NCBI Protein Information
thyrotropin receptor; TSH-R; thyroid-stimulating hormone receptor
UniProt Protein Name
Thyrotropin receptor
Protein Family
UniProt Gene Name
TSHR
UniProt Synonym Gene Names
TSH-R
UniProt Entry Name
TSHR_SHEEP
Uniprot Description
Function: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Subunit structure: Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.Contains 6 LRR (leucine-rich) repeats.
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Product Notes
The TSHR tshr (Catalog #AAA949648) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-413aa; Fragment at the N-terminal, provide the extracellular domain. The amino acid sequence is listed below: ERCPSPPCEC RQEDDFRVTC KDIQRIPSLP PSTQTLKFIE THLKTIPSRA FSNLPNISRI YLSIDATLQQ LESHSFYNLS KVTHIEIRNT RSLTYIDSGA LKELPLLKFL GIFNTGLRVF PDLTKIYSTD VFFILEITDN PYMTSVPANA FQGLSNETLT LKLYNNGFTS IQGHAFNGTK LDAVYLNKNK YLTVIDQDAF AGVYSGPTLL DISYTSVTAL PSKGLEHLKE LIARNTWTLK KLPLSLSFLH LTRADLSYPS HCCAFKNQKN IRGILQSLMC NESSIWGLRQ RKSASALNGP FYQEYEEDLG DGSAGYKENS KFQDTHSNSH YYVFFEDQED EIIGFGQELK NPQEETLQAF DNHYDYTVCG GSEEMVCTPK SDEFNPCEDI MG. It is sometimes possible for the material contained within the vial of "Thyrotropin receptor (TSHR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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