TSHR 420 recombinant protein

Thyroid stimulating hormone receptor 420, TSHR420 Protein (Active)

Cat. Num. AAA355810

• Reactivity: Human
• Applications: ELISA, SDS-Page
• Purity: >90% by SDS-PAGE
• Synonyms: TSHR 420; Thyroid stimulating hormone receptor 420; TSHR420 Protein (Active); Thyrotropin receptor; Thyroid-stimulating hormone receptor; TSH-R; TSHR (200-420 aa); LGR3; TSHR 420 recombinant protein

• Reactivity: Human
• Purity/Purification: >90% by SDS-PAGE
• Form/Format: Liquid
• Sequence Positions: 200-420. Partial Protein.
• Sequence: TKLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LDVSQTSVTA LPSKGLEHLK ELIARNTWTL KKLPLSLSFL HLTRADLSYP SHCCAFKNQK KIRGILESLM CNESSMQSLR QRKSVNALNS PLHQEYEENL GDSIVGYKEK SKFQDTHNNA HYYVFFEEQE DEIIGFGQEL KNPQEETLQA FDSHYDYTIC GDSEDMVCTP KSDEFNPCED IMGYKFLRIV
• Sequence Length: 420

• Applicable Applications for TSHR 420 recombinant protein: ELISA, SDS-PAGE
• Application Notes: Other applications have not been tested.; The optimal dilutions should be determined by end user.
• Preparation and Storage: Ship at 4 degree C. Upon receipt, aliquot and store at -20 degree C or -8O degree C for long term. Avoid repeated freeze and thaw cycles.

Related Product Information for TSHR 420 recombinant protein

Background/Introduction: Thyroid stimulating hormone receptor (TSHR), also known as Thyrotropin receptor is a member of the leucine-rich repeat-containing G protein-coupled receptors. G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. They mediate the effects of several endogenous cues and serve as important pharmacological targets. TSHR is primarily found on the surface of the thyroid epithelial cells. Both TSHR and its ligand TSH have evolved to acquire specificity, minimize cross-reaction to other glycoprotein hormone receptors, and modulate cognate interaction (and thereby thyrotropic activity).