Zinc finger transcription factor Trps1 (TRPS1) Recombinant Protein | TRPS1 recombinant protein

Recombinant Human Zinc finger transcription factor Trps1 (TRPS1) , partial

• Gene Names: TRPS1; GC79; LGCR
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger transcription factor Trps1 (TRPS1); Recombinant Human Zinc finger transcription factor Trps1 (TRPS1); partial; TRPS1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1285

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for TRPS1 recombinant protein

This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.

NCBI and Uniprot Product Information

• NCBI GI #: 544710995
• NCBI GeneID: 7227
• NCBI Accession #: NP_001269831.1
• NCBI GenBank Nucleotide #: NM_001282902.2
• UniProt Accession #: Q9UHF7; Q08AU2; Q9NWE1; Q9UHH6; B4E1Z5
• Molecular Weight: 141,981 Da
• NCBI Official Full Name: zinc finger transcription factor Trps1 isoform 2
• NCBI Official Synonym Full Names: transcriptional repressor GATA binding 1
• NCBI Official Symbol: TRPS1
• NCBI Official Synonym Symbols: GC79; LGCR
• NCBI Protein Information: zinc finger transcription factor Trps1
• UniProt Protein Name: Zinc finger transcription factor Trps1
• Protein Family: Zinc finger transcription factor
• UniProt Gene Name: TRPS1

NCBI Description

This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]

Uniprot Description

Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.