Human transient receptor potential cation channel, subfamily C, member 5 ELISA Kit | TRPC5 elisa kit
Human Short transient receptor potential channel 5, TRPC5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]
Uniprot Description
TRPC5: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC5 sub-subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation
Chromosomal Location of Human Ortholog: Xq23
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; store-operated calcium channel activity; calcium channel activity
Biological Process: nervous system development; axon guidance; calcium ion transport; transmembrane transport
Research Articles on TRPC5
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Product Notes
The Human TRPC5 trpc5 (Catalog #AAA9334703) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334703 ELISA Kit recognizes Human TRPC5. It is sometimes possible for the material contained within the vial of "transient receptor potential cation channel, subfamily C, member 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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