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Pachytene checkpoint protein 2 homolog (TRIP13) Recombinant Protein | TRIP13 recombinant protein

Recombinant Dog Pachytene checkpoint protein 2 homolog (TRIP13)

Gene Names
TRIP13; PCH2; TRIP-13
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pachytene checkpoint protein 2 homolog (TRIP13); Recombinant Dog Pachytene checkpoint protein 2 homolog (TRIP13); TRIP13 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-432, Full length protein
Sequence
MDEAVGDLKQALPCVAEAPTVHVEVHQRSCSTAKKEDIKLSVRKLLNRHNIVFGDYKWNEFDDPFLARNVQSVSIVDTELKVKDPQPIDLGACTIALHVFQLNEGGPSSETLEEETENITAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLIAWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYQYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHCNVVILTTSNITERIDVAFVDRADIRQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPTVTIEGFLQALSLAVDKQFEERKKLSSCI
Sequence Length
432
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for TRIP13 recombinant protein
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,435 Da
NCBI Official Full Name
pachytene checkpoint protein 2 homolog
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 13
NCBI Official Symbol
TRIP13
NCBI Official Synonym Symbols
PCH2; TRIP-13
NCBI Protein Information
pachytene checkpoint protein 2 homolog
UniProt Protein Name
Pachytene checkpoint protein 2 homolog
UniProt Gene Name
TRIP13
UniProt Synonym Gene Names
PCH2; TR-interacting protein 13; TRIP-13

Uniprot Description

Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes ().

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Product Notes

The TRIP13 trip13 (Catalog #AAA1020598) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-432, Full length protein. The amino acid sequence is listed below: MDEAVGDLKQ ALPCVAEAPT VHVEVHQRSC STAKKEDIKL SVRKLLNRHN IVFGDYKWNE FDDPFLARNV QSVSIVDTEL KVKDPQPIDL GACTIALHVF QLNEGGPSSE TLEEETENIT AASHWVLPAA EFHGLWDSLV YDVEVKSHLL DYVMTTLLFS DKNVDSNLIA WNRVVLLHGP PGTGKTSLCK ALAQKLTIRL SSRYQYGQLI EINSHSLFSK WFSESGKLVT KMFQKIQDLI DDKDALVFVL IDEVESLTAA RNACRAGTEP SDAIRVVNAV LTQIDQIKRH CNVVILTTSN ITERIDVAFV DRADIRQYIG PPSAAAIFKI YLSCLEELMK CQIIYPRQQL LTLRELEMIG FIENNVSKLS LLLSEISRKS EGLSGRVLRK LPFLAHALYI QAPTVTIEGF LQALSLAVDK QFEERKKLSS CI. It is sometimes possible for the material contained within the vial of "Pachytene checkpoint protein 2 homolog (TRIP13), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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