Tropomyosin alpha-3 chain (Tpm3) Recombinant Protein | Tpm3 recombinant protein
Recombinant Rat Tropomyosin alpha-3 chain (Tpm3)
Gene Names
Tpm3; Tpm5; TM30nm
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Tropomyosin alpha-3 chain (Tpm3); Recombinant Rat Tropomyosin alpha-3 chain (Tpm3); Tpm3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-248, full length protein
Sequence
AGSTTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM
Sequence Length
247
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Tpm3 recombinant protein
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,709 Da
NCBI Official Full Name
tropomyosin alpha-3 chain Tpm3.3cy
NCBI Official Synonym Full Names
tropomyosin 3
NCBI Official Symbol
Tpm3
NCBI Official Synonym Symbols
Tpm5; TM30nm
NCBI Protein Information
tropomyosin alpha-3 chain
UniProt Protein Name
Tropomyosin alpha-3 chain
Protein Family
UniProt Gene Name
Tpm3
UniProt Synonym Gene Names
Tpm-5; Tpm5
NCBI Description
rod-like protein associated with actin filament in nonmuscle cells; may mediate the stability of actin filaments; may play a role in the regulation of cell transformation, cytokinesis, motility, and morphogenesis [RGD, Feb 2006]
Uniprot Description
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Research Articles on Tpm3
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Product Notes
The Tpm3 tpm3 (Catalog #AAA1372743) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-248, full length protein. The amino acid sequence is listed below: AGSTTIEAVK RKIQVLQQQA DDAEERAERL QREVEGERRA REQAEAEVAS LNRRIQLVEE ELDRAQERLA TALQKLEEAE KAADESERGM KVIENRALKD EEKMELQEIQ LKEAKHIAEE ADRKYEEVAR KLVIIEGDLE RTEERAELAE SRCREMDEQI RLMDQNLKCL SAAEEKYSQK EDKYEEEIKI LTDKLKEAET RAEFAERSVA KLEKTIDDLE DKLKCTKEEH LCTQRMLDQT LLDLNEM. It is sometimes possible for the material contained within the vial of "Tropomyosin alpha-3 chain (Tpm3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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