SDS-Page
Troponin C Recombinant Protein | TNNC2 recombinant protein
Troponin C 1-160aa, Human, E Coli
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Troponin C; Troponin C 1-160aa; Human; E Coli; Troponin C skeletal muscle; skeletal muscle; TNNC2; skeletal muscle TNNC1; Cardiac troponin C; TNNC; Troponin C1 slow; Fast skeletal muscle troponin C; Skeletal troponin C; Troponin C type 1 (slow); Troponin C type 2 (fast); slow skeletal and cardiac muscles; ; TNNC2 recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% glycerol.
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ
Sequence Length
160
Applicable Applications for TNNC2 recombinant protein
SDS-PAGE
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for TNNC2 recombinant protein
Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I (Tn-1), Troponin T (Tn-T) and Troponin C (Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for TNNC2 recombinant protein
References
Prentice H., et al. (1994). J Mol Cell Cardial. 26 (10):1393-401. ; Gahlmann R., et al. (1988). J Mol Biol. 201 (2):379-91. ; Li Y., et al. (2008). Hereditas. 145 (6):274-82.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18.1 kDa (160aa), confirmed by MALDI-TOF.
NCBI Official Full Name
troponin C, skeletal muscle
NCBI Official Synonym Full Names
troponin C2, fast skeletal type
NCBI Official Symbol
TNNC2
NCBI Protein Information
troponin C, skeletal muscle
UniProt Protein Name
Troponin C, skeletal muscle
Protein Family
UniProt Gene Name
TNNC2
NCBI Description
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
Uniprot Description
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Research Articles on TNNC2
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Product Notes
The TNNC2 tnnc2 (Catalog #AAA203333) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Troponin C can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the TNNC2 tnnc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ. It is sometimes possible for the material contained within the vial of "Troponin C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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