Mouse transmembrane protease, serine 3 ELISA Kit | TMPRSS3 elisa kit
Mouse Transmembrane protease serine 3, TMPRSS3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TMPRSS3: Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro). Defects in TMPRSS3 are the cause of deafness autosomal recessive type 8 (DFNB8). DFNA8 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Defects in TMPRSS3 are the cause of deafness autosomal recessive type 10 (DFNB10). Belongs to the peptidase S1 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.-; Membrane protein, integral; Protease; Endoplasmic reticulum
Cellular Component: endoplasmic reticulum membrane; membrane; cell soma; endoplasmic reticulum; integral to membrane
Molecular Function: peptidase activity; sodium channel regulator activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity; scavenger receptor activity
Biological Process: cellular sodium ion homeostasis; sensory perception of sound; proteolysis
Research Articles on TMPRSS3
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Product Notes
The Mouse TMPRSS3 tmprss3 (Catalog #AAA9322960) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322960 ELISA Kit recognizes Mouse TMPRSS3. It is sometimes possible for the material contained within the vial of "transmembrane protease, serine 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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