Toll-like receptor 2 (TLR2) Recombinant Protein | TLR2 recombinant protein
Recombinant Macaca mulatta Toll-like receptor 2 (TLR2), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Toll-like receptor 2 (TLR2); Recombinant Macaca mulatta Toll-like receptor 2 (TLR2); partial; Toll-like receptor 2; CD_antigen=; CD282; TLR2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
21-587aa; Partial, provide the complete extracellular domain.
Sequence
ESSNQASLSCDHNGICKGSSGSLNSIPSVLTEAVKCLDLSNNRITYISNSDLQRYVNLQALVLTSNGINTIEEDSFSSLGRLEHLDLSYNYLSNLSSSWFKPLSSLKFLNLLGNPYKTLGETSLFSHLTKLRILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDLTSSVECLELRDTDLNTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLSQISGLLELEFDDCTLNGVGDFRGSDNDRVIDPGKVETLTIRRLHIPQFYSFNDLSTLYPLTERVKRITVENSKVFLVPCLLSRHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLGKIGETLLTLKNLTNLDISKNTFHYMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDISNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNTITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLVDWPANYLCDSPSHVRGQRVQDVRLSVSECHR
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90,071 Da
NCBI Official Full Name
toll-like receptor 2
NCBI Official Symbol
TLR2
NCBI Protein Information
toll-like receptor 2
UniProt Protein Name
Toll-like receptor 2
Protein Family
UniProt Gene Name
TLR2
UniProt Entry Name
TLR2_MACMU
Uniprot Description
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides ().
Research Articles on TLR2
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Product Notes
The TLR2 tlr2 (Catalog #AAA1409101) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-587aa; Partial, provide the complete extracellular domain. The amino acid sequence is listed below: ESSNQASLSC DHNGICKGSS GSLNSIPSVL TEAVKCLDLS NNRITYISNS DLQRYVNLQA LVLTSNGINT IEEDSFSSLG RLEHLDLSYN YLSNLSSSWF KPLSSLKFLN LLGNPYKTLG ETSLFSHLTK LRILRVGNMD TFTKIQRKDF AGLTFLEELE IDASDLQSYE PKSLKSIQNV SHLILHMKQH ILLLEIFVDL TSSVECLELR DTDLNTFHFS ELSTGETNSL IKKFTFRNVK ITDESLFQVM KLLSQISGLL ELEFDDCTLN GVGDFRGSDN DRVIDPGKVE TLTIRRLHIP QFYSFNDLST LYPLTERVKR ITVENSKVFL VPCLLSRHLK SLEYLDLSEN LMVEEYLKNS ACEDAWPSLQ TLILRQNHLA SLGKIGETLL TLKNLTNLDI SKNTFHYMPE TCQWPEKMKY LNLSSTRIHS VTGCIPKTLE ILDISNNNLN LFSLNLPQLK ELYISRNKLM TLPDASLLPM LLVLKISRNT ITTFSKEQLD SFHTLKTLEA GGNNFICSCE FLSFTQEQQA LAKVLVDWPA NYLCDSPSHV RGQRVQDVRL SVSECHR. It is sometimes possible for the material contained within the vial of "Toll-like receptor 2 (TLR2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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