SDS-Page
MESDC1 recombinant protein
MESDC1, 1-362aa, Human, His tag, E Coli
Gene Names
TLNRD1; MESDC1
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
MESDC1; 1-362aa; Human; His tag; E Coli; Mesoderm development candidate 1; MGC99595; MESDC1 recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Concentration
0.5 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMASGSAG KPTGEAASPA PASAIGGASS QPRKRLVSVC DHCKGKMQLV ADLLLLSSEA RPVLFEGPAS SGAGAESFEQ CRDTIIARTK GLSILTHDVQ SQLNMGRFGE AGDSLVELGD LVVSLTECSA HAAYLAAVAT PGAQPAQPGL VDRYRVTRCR HEVEQGCAVL RATPLADMTP QLLLEVSQGL SRNLKFLTDA CALASDKSRD RFSREQFKLG VKCMSTSASA LLACVREVKV APSELARSRC ALFSGPLVQA VSALVGFATE PQFLGRAAAV SAEGKAVQTA ILGGAMSVVS ACVLLTQCLR DLAQHPDGGA KMSDHRERLR NSACAVSEGC TLLSQALRER SSPRTLPPVN SNSVN
Sequence Length
362
Applicable Applications for MESDC1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for MESDC1 recombinant protein
Mesoderm development candidate 1, also known as MESDC1, belongs to the MESD family. It is a 362 amino acid protein encoded by a gene that maps to human chromosome 15q25.1. MESDC1 acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6). MESDC1 is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. Recombinant human MESDC1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for MESDC1 recombinant protein
References
Wines M E., et al. (2001) Genomics.72: 88-98.; Midia G S., et al. (2008) JAAPA. 21: 21-25.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40.1 kDa (385aa) confirmed by MALDI-TOF
NCBI Official Full Name
talin rod domain-containing protein 1
NCBI Official Synonym Full Names
talin rod domain containing 1
NCBI Official Symbol
TLNRD1
NCBI Official Synonym Symbols
MESDC1
NCBI Protein Information
talin rod domain-containing protein 1
UniProt Protein Name
Talin rod domain-containing protein 1
Protein Family
UniProt Gene Name
TLNRD1
NCBI Description
This gene encodes a protein that is regulated by micro RNA MiR-574-3, and is thought to have an oncogenic function in human bladder cancer. A similar gene in mouse is located in a chromosomal region critical for differentiation of mesoderm, which affects embryo patterning and the formation of heart, muscle, blood, skeleton and the urogenital system. The mouse gene is expressed in early development, and in the adult. [provided by RefSeq, Nov 2016]
Uniprot Description
Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells.
Research Articles on MESDC1
Similar Products
Product Notes
The MESDC1 tlnrd1 (Catalog #AAA205658) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's MESDC1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the MESDC1 tlnrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMASGSAG KPTGEAASPA PASAIGGASS QPRKRLVSVC DHCKGKMQLV ADLLLLSSEA RPVLFEGPAS SGAGAESFEQ CRDTIIARTK GLSILTHDVQ SQLNMGRFGE AGDSLVELGD LVVSLTECSA HAAYLAAVAT PGAQPAQPGL VDRYRVTRCR HEVEQGCAVL RATPLADMTP QLLLEVSQGL SRNLKFLTDA CALASDKSRD RFSREQFKLG VKCMSTSASA LLACVREVKV APSELARSRC ALFSGPLVQA VSALVGFATE PQFLGRAAAV SAEGKAVQTA ILGGAMSVVS ACVLLTQCLR DLAQHPDGGA KMSDHRERLR NSACAVSEGC TLLSQALRER SSPRTLPPVN SNSVN. It is sometimes possible for the material contained within the vial of "MESDC1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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