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Mitochondrial import inner membrane translocase subunit TIM54 (TIM54) Recombinant Protein | TIM54 recombinant protein

Recombinant Saccharomyces cerevisiae Mitochondrial import inner membrane translocase subunit TIM54 (TIM54)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Mitochondrial import inner membrane translocase subunit TIM54 (TIM54); Recombinant Saccharomyces cerevisiae Mitochondrial import inner membrane translocase subunit TIM54 (TIM54); Recombinant Mitochondrial import inner membrane translocase subunit TIM54 (TIM54); Mitochondrial import inner membrane translocase subunit TIM54; TIM54 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-478
Sequence
MSSESGKPIAKPIRKPGYTNPALKALGIPALRLPSRNWMIFWSVLTVSIGGIAYDKYKQRQILSHATDLVKPLAEESMEVDKVPRKITVFIAPPPNDYLESSLKVWRRYVKPVLYYAGLDYELVQEDRQGIIRTNVANRIRELRKEILASTDGQPVKEPNQTVAKPSGSSTSKISSLLPFNKIIQDPAEEDDSFDPEIGKKFKENFDWRNVIGIFYTMPKPKHIISEDALTKDPILSGGVICLGRGAYKEYIAGIHEGLLGPIEKTEKTGSTEPKMTGVVEANQIESKVSESGATELVDAEKETALEEAKVQDDLKVDEENSSEDSQKFLKPFISSDQYPDLQIASELQTPNGEFIRNPNTNIPLLINQPLLVIPIPNLIGFTTIPRRIHRFYQKRFYVEDVCSSVVNCVRQTRIRPFDIAKDIDLAKDEEKDWPQNWVKQGKEKNSEWTQELVCDPRITKHMFVYEKPPKEEPESDI
Sequence Length
478
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,183 Da
NCBI Official Full Name
Tim54p
NCBI Official Symbol
TIM54
NCBI Protein Information
Tim54p
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM54
UniProt Gene Name
TIM54
UniProt Entry Name
TIM54_YEAST

Uniprot Description

Function: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its precise function within the TIM22 complex is unclear. Ref.3 Ref.5 Ref.7

Subunit structure: Component of the TIM22 complex, whose core is composed of TIM18, TIM22 and TIM54, associated with the peripheral proteins MRS5/TIM12 and the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13). Ref.5 Ref.6 Ref.9

Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein. Note: Import into inner membrane protein requires TOM70 function. Ref.3 Ref.4 Ref.5 Ref.8

Sequence similarities: Belongs to the TIM54 family.

Research Articles on TIM54

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Product Notes

The TIM54 tim54 (Catalog #AAA1057041) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-478. The amino acid sequence is listed below: MSSESGKPIA KPIRKPGYTN PALKALGIPA LRLPSRNWMI FWSVLTVSIG GIAYDKYKQR QILSHATDLV KPLAEESMEV DKVPRKITVF IAPPPNDYLE SSLKVWRRYV KPVLYYAGLD YELVQEDRQG IIRTNVANRI RELRKEILAS TDGQPVKEPN QTVAKPSGSS TSKISSLLPF NKIIQDPAEE DDSFDPEIGK KFKENFDWRN VIGIFYTMPK PKHIISEDAL TKDPILSGGV ICLGRGAYKE YIAGIHEGLL GPIEKTEKTG STEPKMTGVV EANQIESKVS ESGATELVDA EKETALEEAK VQDDLKVDEE NSSEDSQKFL KPFISSDQYP DLQIASELQT PNGEFIRNPN TNIPLLINQP LLVIPIPNLI GFTTIPRRIH RFYQKRFYVE DVCSSVVNCV RQTRIRPFDI AKDIDLAKDE EKDWPQNWVK QGKEKNSEWT QELVCDPRIT KHMFVYEKPP KEEPESDI. It is sometimes possible for the material contained within the vial of "Mitochondrial import inner membrane translocase subunit TIM54 (TIM54), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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