Human T-cell lymphoma invasion and metastasis 1 ELISA Kit | TIAM1 elisa kit
Human T-lymphoma invasion and metastasis-inducing protein 1, TIAM1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TIAM1: modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Regulates migration, cell-matrix and cell-cell adhesion by modulating the actin cytoskeleton through the GTPase, Rac1. Binding to Rac1 and the Arp2/3 complex may drive actin polymerization at specific sites, thus inducing dynamic morphological changes.
Protein type: Motility/polarity/chemotaxis; GEFs, Rac/Rho; Oncoprotein; GEFs
Chromosomal Location of Human Ortholog: 21q22.11
Cellular Component: extrinsic to internal side of plasma membrane; intercellular junction; cytosol
Molecular Function: Rho guanyl-nucleotide exchange factor activity; ephrin receptor binding; Rac guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; receptor signaling protein activity; phospholipid binding
Biological Process: axon guidance; cell migration; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; cell-matrix adhesion; small GTPase mediated signal transduction; ephrin receptor signaling pathway; Rac protein signal transduction; positive regulation of axonogenesis
Research Articles on TIAM1
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Product Notes
The Human TIAM1 tiam1 (Catalog #AAA9335654) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335654 ELISA Kit recognizes Human TIAM1. It is sometimes possible for the material contained within the vial of "T-cell lymphoma invasion and metastasis 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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