Rat transforming growth factor, beta receptor II (70/80kDa) ELISA Kit | TGFBR2 elisa kit
Rat transforming growth factor beta2 receptor, TGF-beta2R ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
receptor for TGF-beta; may play a role in lung maturation and response to hypoxia [RGD, Feb 2006]
Uniprot Description
TGFBR2: a TKL kinase of the serine/threonine-protein kinase receptor (STKR) family. R1 and R2 TGF-beta receptors dimerize after binding TGF-beta at the cell surface. Binds to DAXX. Defects can cause esophageal cancer.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (receptor); Oncoprotein; EC 2.7.11.30; Membrane protein, integral; Protein kinase, TKL; TKL group; STKR family; Type2 subfamily
Cellular Component: cell surface; integral to plasma membrane; cytoplasm; integral to membrane; caveola; cytosol; receptor complex; lipid raft; external side of plasma membrane
Molecular Function: transforming growth factor beta receptor activity; protein binding; glycosaminoglycan binding; protein homodimerization activity; transforming growth factor beta receptor activity, type II; protein heterodimerization activity; transforming growth factor beta binding; metal ion binding; mitogen-activated protein kinase kinase kinase binding; SMAD binding; transmembrane receptor protein serine/threonine kinase activity; ATP binding; receptor signaling protein serine/threonine kinase activity
Biological Process: heart development; gastrulation; protein amino acid phosphorylation; response to organic cyclic substance; transforming growth factor beta receptor signaling pathway; positive regulation of mesenchymal cell proliferation; transmembrane receptor protein serine/threonine kinase signaling pathway; response to glucose stimulus; positive regulation of NK T cell differentiation; positive regulation of T cell tolerance induction; response to drug; organ regeneration; embryonic hemopoiesis; embryonic cranial skeleton morphogenesis; patterning of blood vessels; positive regulation of angiogenesis; organ morphogenesis; response to mechanical stimulus; regulation of gene expression; response to estrogen stimulus; response to steroid hormone stimulus; activation of protein kinase activity; lens development in camera-type eye; wound healing; apoptosis; positive regulation of smooth muscle cell proliferation; myeloid dendritic cell differentiation; palate development; positive regulation of tolerance induction to self antigen; response to organic substance; negative regulation of cell proliferation; negative regulation of cardiac muscle cell proliferation; vasculogenesis; response to nutrient; aging; receptor-mediated endocytosis; smoothened signaling pathway; positive regulation of skeletal muscle regeneration; in utero embryonic development; common-partner SMAD protein phosphorylation; peptidyl-threonine phosphorylation; regulation of cell proliferation; peptidyl-serine phosphorylation; gut development; cartilage development; positive regulation of B cell tolerance induction; response to hypoxia; brain development; embryo implantation; lung development
Research Articles on TGFBR2
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Product Notes
The Rat TGFBR2 tgfbr2 (Catalog #AAA9310009) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9310009 ELISA Kit recognizes Rat TGFBR2. It is sometimes possible for the material contained within the vial of "transforming growth factor, beta receptor II (70/80kDa), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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