Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Transglutaminase 2 antibody.)
anti-Human, Mouse Transglutaminase 2 Antibody | anti-TGC antibody
Transglutaminase 2 Antibody
Gene Names
TGM2; TGC; TG(C)
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Transglutaminase 2; Transglutaminase 2 Antibody; Protein-glutamine gamma-glutamyltransferase; TG(C); TGase C; TGase-H; Tissue transglutaminase; transglutaminase 2; anti-TGC antibody
Reactivity
Human, Mouse
Specificity
Transglutaminase 2 antibody detects endogenous levels of total Transglutaminase 2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
687
Applicable Applications for anti-TGC antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:5000
IHC: 1:50~1:100
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from human Transglutaminase 2 antibody.
Preparation and Storage
Store at-20 degree C for 1 year
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Transglutaminase 2 antibody.)
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Transglutaminase 2 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HuvEc cells, using Transglutaminase 2 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HuvEc cells, using Transglutaminase 2 antibody.)
Product Categories/Family for anti-TGC antibody
References
Liya Yuan, Mol. Cancer Ther., Sep 2005; 4: 1293-1302. Luba Eligula, Biophys. J., Feb 1998; 74: 953-963. Azin Agah, Am. J. Pathol., Jul 2005; 167: 81-88. Gina M. Zainelli, J. Neurosci., Feb 2004; 24: 1954.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,671 Da
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase 2 isoform a
NCBI Official Synonym Full Names
transglutaminase 2
NCBI Official Symbol
TGM2
NCBI Official Synonym Symbols
TGC; TG(C)
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 2
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase 2
UniProt Gene Name
TGM2
UniProt Synonym Gene Names
TG(C); TGC; TGase C; TGase H; TGase-2
NCBI Description
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Research Articles on TGC
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Product Notes
The TGC tgm2 (Catalog #AAA855524) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Transglutaminase 2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Transglutaminase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000. Researchers should empirically determine the suitability of the TGC tgm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transglutaminase 2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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