Probable RNA polymerase II transcription factor B subunit 1-3 (TFB1-3) Recombinant Protein | TFB1-3 recombinant protein

Recombinant Arabidopsis thaliana Probable RNA polymerase II transcription factor B subunit 1-3 (TFB1-3) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable RNA polymerase II transcription factor B subunit 1-3 (TFB1-3); Recombinant Arabidopsis thaliana Probable RNA polymerase II transcription factor B subunit 1-3 (TFB1-3); partial; TFB1-3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 579

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 240255685
• NCBI GeneID: 825315
• NCBI Accession #: NP_191701.4
• NCBI GenBank Nucleotide #: NM_116007.5
• UniProt Accession #: Q9M322; Q5BIV2; Q67Y79
• Molecular Weight: 27,680 Da
• NCBI Official Full Name: BSD domain (BTF2-like transcription factors, Synapse-associated proteins and DOS2-like proteins)
• NCBI Official Symbol: AT3G61420
• NCBI Protein Information: BSD domain (BTF2-like transcription factors, Synapse-associated proteins and DOS2-like proteins)
• UniProt Protein Name: General transcription and DNA repair factor IIH subunit TFB1-3
• Protein Family: Probable RNA polymerase II transcription factor
• UniProt Gene Name: TFB1-3
• UniProt Synonym Gene Names: GTF2H1-2Curated; TFIIH subunit TFB1-3

Uniprot Description

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.