Mouse transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) ELISA Kit | TFAP2C elisa kit
Mouse Transcription factor AP-2 gamma, TFAP2C ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
AP-2 gamma: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity. During retinoic acid-mediated differentiation. Belongs to the AP-2 family.
Protein type: DNA-binding; Transcription factor; Motility/polarity/chemotaxis
Cellular Component: nucleus
Molecular Function: protein dimerization activity; protein binding; DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; skin development; transcription, DNA-dependent; somatic stem cell maintenance; stem cell maintenance; germ-line stem cell maintenance; sebaceous gland development; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic; trophectodermal cell differentiation; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; hair follicle development; positive regulation of transcription from RNA polymerase II promoter; forebrain neuron fate commitment; cerebral cortex development; cell differentiation; regulation of epidermis development
Research Articles on TFAP2C
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Product Notes
The Mouse TFAP2C tfap2c (Catalog #AAA9334711) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334711 ELISA Kit recognizes Mouse TFAP2C. It is sometimes possible for the material contained within the vial of "transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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