Trichoplein keratin filament-binding protein (TCHP) Recombinant Protein | TCHP recombinant protein
Recombinant Pongo abelii Trichoplein keratin filament-binding protein (TCHP)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Trichoplein keratin filament-binding protein (TCHP); Recombinant Pongo abelii Trichoplein keratin filament-binding protein (TCHP); TCHP recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-498, Full length protein
Sequence
MALPTLPFYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMREEQDLLARELEELRLSMNLQERRIREQHRKLKSAREEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVINSWETQKEEKKQQEATAEEENKRYENEYERAQREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLNRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVIADAAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEARESARREKEENEELKSARKQELEAQVAERQLQAWEADQQEKEEEEEARRVEQLSDALLQQEAETMAEQGYRPKPYGHPKIAWN
Sequence Length
498
Species
Pongo abelii (Sumatran orangutan)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61,170 Da
NCBI Official Full Name
trichoplein keratin filament-binding protein
NCBI Official Symbol
TCHP
NCBI Protein Information
trichoplein keratin filament-binding protein
UniProt Protein Name
Trichoplein keratin filament-binding protein
Protein Family
UniProt Gene Name
TCHP
UniProt Synonym Gene Names
Protein TCHP; Mitostatin
Uniprot Description
Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (). Is a negative regulator of ciliogenesis ().
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Product Notes
The TCHP tchp (Catalog #AAA1458568) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-498, Full length protein. The amino acid sequence is listed below: MALPTLPFYW CSQQRLNQQL ARQREQEARL RQQWEQNSRY FRMSDICSSK QAEWSSKTSY QRSMHAYQRE KMKEEKRRSL EARREKLRQL MREEQDLLAR ELEELRLSMN LQERRIREQH RKLKSAREEQ RKLIAEQLLY EHWKKNNPKL REMELDLHQK HVINSWETQK EEKKQQEATA EEENKRYENE YERAQREALE RMKAEEERRQ LEDKLQAEAL LQQMEELKLK EVEATKLKKE QENLLKQRWE LERLEEERKQ MEAFRQKAEL GRFLRHQYNA QLNRRTQQIQ EELEADRRIL QALLEKEDES QRLHLARREQ VIADAAWMKQ AIEEQLQLER AREAELQMLL REEAKEMWEK REAEWARERS ARDRLMSEVL TGRQQQIQEK IEQNRRAQEE SLKHREQLIR NLEEARESAR REKEENEELK SARKQELEAQ VAERQLQAWE ADQQEKEEEE EARRVEQLSD ALLQQEAETM AEQGYRPKPY GHPKIAWN. It is sometimes possible for the material contained within the vial of "Trichoplein keratin filament-binding protein (TCHP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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