Transcription elongation factor A protein 2 Recombinant Protein | TCEA2 recombinant protein

Recombinant Human Transcription elongation factor A protein 2

Cat. Num. AAA9421149

• Gene Names: TCEA2; TFIIS
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Transcription elongation factor A protein 2; Recombinant Human Transcription elongation factor A protein 2; Testis-specific S-IITranscription elongation factor S-II protein 2Transcription elongation factor TFIIS.l; TCEA2 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Full Length, 1-299aa

• Tag Info: His-SUMO-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for TCEA2 recombinant protein

Necessary for efficient RNA polymerase II transcription elongation past tplate-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 4507385
• NCBI GeneID: 6919
• NCBI Accession #: NP_003186.1
• NCBI GenBank Nucleotide #: NM_003195.5
• UniProt Accession #: Q15560; Q8TD37; Q8TD38; B3KNM1
• Molecular Weight: 49.6kD
• NCBI Official Full Name: transcription elongation factor A protein 2 isoform a
• NCBI Official Synonym Full Names: transcription elongation factor A2
• NCBI Official Symbol: TCEA2
• NCBI Official Synonym Symbols: TFIIS
• NCBI Protein Information: transcription elongation factor A protein 2
• UniProt Protein Name: Transcription elongation factor A protein 2
• Protein Family: Tuliposide A-converting enzyme
• UniProt Gene Name: TCEA2

NCBI Description

The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TCEA2: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Belongs to the TFS-II family.

Chromosomal Location of Human Ortholog: 20q13.33

Molecular Function: protein binding