Tubulin-specific chaperone C Recombinant Protein | TBCC recombinant protein
Recombinant Human Tubulin-specific chaperone C
NCBI and Uniprot Product Information
NCBI Description
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
Uniprot Description
TBCC: Tubulin-folding protein; involved in the final step of the tubulin folding pathway. Belongs to the TBCC family.
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: cytoplasm; cytoskeleton; microtubule; photoreceptor connecting cilium
Molecular Function: chaperone binding; GTPase activity; tubulin binding
Biological Process: 'de novo' posttranslational protein folding; cell morphogenesis; cellular protein metabolic process; post-chaperonin tubulin folding pathway; protein folding
Research Articles on TBCC
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Product Notes
The TBCC tbcc (Catalog #AAA969620) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-345aa; Full Length. The amino acid sequence is listed below: ESVSCSAAAV RTGDMESQRD LSLVPERLQR REQERQLEVE RRKQKRQNQE VEKENSHFFV ATFVRERAAV EELLERAESV ERLEEAASRL QGLQKLINDS VFFLAAYDLR QGQEALARLQ AALAERRRGL QPKKRFAFKT RGKDAASSTK VDAAPGIPPA VESIQDSPLP KKAEGDLGPS WVCGFSNLES QVLEKRASEL HQRDVLLTEL SNCTVRLYGN PNTLRLTKAH SCKLLCGPVS TSVFLEDCSD CVLAVACQQL RIHSTKDTRI FLQVTSRAIV EDCSGIQFAP YTWSYPEIDK DFESSGLDRS KNNWNDVDDF NWLARDMASP NWSILPEEER NIQW. It is sometimes possible for the material contained within the vial of "Tubulin-specific chaperone C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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