Sec-independent protein translocase protein TatCd (tatC1) Recombinant Protein | tatCD recombinant protein
Recombinant Bacillus subtilis Sec-independent protein translocase protein TatCd (tatC1)
NCBI and Uniprot Product Information
Uniprot Description
Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance. Ref.9
Subunit structure: Forms a complex with TatAd. Two types of complexes exist: one composed of TatAd and TatCd, and another composed only of TatAd. Ref.9
Subcellular location: Cell membrane; Multi-pass membrane protein Ref.6.
Induction: Expressed under conditions of phosphate starvation. HAMAP-Rule MF_00902
Disruption phenotype: Depletion of TatCd results in a drastic reduction of TatAd. Ref.8
Miscellaneous: B.subtilis possesses two minimal, substrate-specific, Tat translocases: TatAd-TatCd and TatAy-TatCy, each one composed of a TatA and a TatC protein. TatA is bifunctional and performs the function of both the TatA and TatB proteins of Gram-negative organisms. HAMAP-Rule MF_00902
Sequence similarities: Belongs to the TatC family.
Sequence caution: The sequence BAA06484.1 differs from that shown. Reason: Frameshift at position 20.
Research Articles on tatCD
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Product Notes
The tatCD tatc1 (Catalog #AAA1096012) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-242. The amino acid sequence is listed below: MDKKETHLIG HLEELRRRII VTLAAFFLFL ITAFLFVQDI YDWLIRDLDG KLAVLGPSEI LWVYMMLSGI CAIAASIPVA AYQLWRFVAP ALTKTERKVT LMYIPGLFAL FLAGISFGYF VLFPIVLSFL THLSSGHFET MFTADRYFRF MVNLSLPFGF LFEMPLVVMF LTRLGILNPY RLAKARKLSY FLLIVVSILI TPPDFISDFL VMIPLLVLFE VSVTLSAFVY KKRMREETAA AA. It is sometimes possible for the material contained within the vial of "Sec-independent protein translocase protein TatCd (tatC1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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