Horse TATA Box Binding Protein Associated Factor 12 ELISA Kit | TAF12 elisa kit

Horse TATA Box Binding Protein Associated Factor 12 ELISA Kit

Cat. Num. AAA104631

• Gene Names: TAF12; TAF2J; TAFII20
• Reactivity: Horse
• Synonyms: TATA Box Binding Protein Associated Factor 12; Horse TATA Box Binding Protein Associated Factor 12 ELISA Kit; TAF12 elisa kit

• Reactivity: Horse
• Sequence Length: 161

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 119628088
• NCBI GeneID: 6883
• UniProt Accession #: Q16514; Q15775; Q5T077; D3DPM5
• Molecular Weight: 17,924 Da
• NCBI Official Full Name: TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa, isoform CRA_c
• NCBI Official Synonym Full Names: TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
• NCBI Official Symbol: TAF12
• NCBI Official Synonym Symbols: TAF2J; TAFII20
• NCBI Protein Information: transcription initiation factor TFIID subunit 12; TAFII20/TAFII15; TAFII-20/TAFII-15; transcription initiation factor TFIID 20/15 kDa subunits; TATA box binding protein (TBP)-associated factor, RNA polymerase II, J, 20kD
• UniProt Protein Name: Transcription initiation factor TFIID subunit 12
• Protein Family: Transcription initiation factor
• UniProt Gene Name: TAF12
• UniProt Synonym Gene Names: TAF15; TAF2J; TAFII20; TAFII-20/TAFII-15
• UniProt Entry Name: TAF12_HUMAN

NCBI Description

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]

Uniprot Description

TAF12: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. Belongs to the TAF12 family. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: nucleoplasm; PCAF complex; transcription factor TFIID complex

Molecular Function: protein binding; histone acetyltransferase activity; DNA binding; protein heterodimerization activity; transcription coactivator activity; transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; viral reproduction; RNA elongation from RNA polymerase II promoter; transcription initiation; positive regulation of transcription factor activity; gene expression