NCBI and Uniprot Product Information
NCBI Description
may play a role in synaptic vesicle organization and synaptic plasticity [RGD, Feb 2006]
Uniprot Description
SYP: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Homohexamer or homotetramer. Interacts with SRCIN1. Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. Belongs to the synaptophysin/synaptobrevin family.
Protein type: Vesicle; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: cell junction; excitatory synapse; integral to membrane; integral to synaptic vesicle membrane; intracellular organelle; membrane; neuron projection; presynaptic active zone; presynaptic membrane; protein complex; synapse; synaptic vesicle; synaptic vesicle membrane; terminal button
Molecular Function: cholesterol binding; identical protein binding; protein binding; protein complex binding; protein domain specific binding; SH2 domain binding; syntaxin-1 binding; transporter activity
Biological Process: endocytosis; regulation of long-term neuronal synaptic plasticity; regulation of neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; transport
Research Articles on Syp
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Product Notes
The Rat Syp syp (Catalog #AAA2887098) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887098 ELISA Kit recognizes Rat Syp. It is sometimes possible for the material contained within the vial of "Synaptophysin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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