Chemical Structure
(Chemical structure of SAHA (Vorinostat) (SIH-359), a HDAC inhibitor. CAS #: 149647-78-9. Molecular Formula: C14H20N2O3. Molecular Weight: 264.3 g/mol.)
SAHA small molecule
SAHA (Vorinostat)
Purity
>98% (TLC), NMR conforms
Synonyms
SAHA; SAHA (Vorinostat); HDAC inhibitor; Suberoylanilide-hydroxamic acid; Vorinostat; N-Hydroxy-N'-phenyloctanediamide; SAHA small molecule
Host
Synthetic
Purity/Purification
>98% (TLC), NMR conforms
Form/Format
White solid
Sequence Length
469
Solubility
Soluble in 50 mg/ml DMSO, or 2 mg/ml Ethanol
CAS Number
149647-78-9
Molecular Formula
C14H20N2O3
SMILES
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
InChI
1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChI Key
WAEXFXRVDQXREF-UHFFFAOYSA-N
PubChem CID
5311
Preparation and Storage
Store at -20 degree C.
Chemical Structure
(Chemical structure of SAHA (Vorinostat) (SIH-359), a HDAC inhibitor. CAS #: 149647-78-9. Molecular Formula: C14H20N2O3. Molecular Weight: 264.3 g/mol.)
Chemical Structure
(Chemical structure of SAHA (Vorinostat) (SIH-359), a HDAC inhibitor. CAS #: 149647-78-9. Molecular Formula: C14H20N2O3. Molecular Weight: 264.3 g/mol.)
Related Product Information for SAHA small molecule
Potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. Synergizes with kinase inhibitors to kill CNS tumor cells. Cell permeable.
Product Categories/Family for SAHA small molecule
References
1. Vrana J.A., et al., (1999) Oncogene. 18: 7016. 2. Butler L.M., et al., (2002) Proc. Natl. Acad. Sci. USA. 99: 11700. 3. Tang Y., et al., (2012) Cancer Biol. Ther. 2012 13(7): 567-574.
NCBI and Uniprot Product Information
Uniprot Description
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
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Product Notes
The SAHA saha (Catalog #AAA808063) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SAHA, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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