Thymic Factor Steroid
Thymic Factor (Thymulin, Serum Thymic Factor, STF, Facteur Thymique Serique)
Purity
Highly Purified~95%. Purified by HPLC.
Synonyms
Thymic Factor; Thymic Factor (Thymulin; Serum Thymic Factor; STF; Facteur Thymique Serique); Thymic Factor steroid
Host
Synthetic peptide
Purity/Purification
Highly Purified
~95%. Purified by HPLC.
~95%. Purified by HPLC.
Form/Format
Supplied as a lyophilized powder.
Sequence (linear)
Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Thymic Factor steroid
Thymulin (also known as Thymic Factor or under its old name Facteur Thymique Serique) is a nonapeptide produced by two distinct epithelial populations in the thymus first described by Bach in 1977.[1] It requires zinc for biological activity. The hormone is believed to be involved in T-cell differentiation and enhancement of T and NK cell actions.[1] Besides this rather paracrine or auto-organic effects on the thymus dependent immune system, Thymulin seems to have neuroendocrine effects as well. There exist bidirectional interactions between thymic epithelium and the hypothalamus-pituitary axis (for example, thymulin follows a circadian rhythm and physiologically elevated ACTH levels correlate positively with thymulin plasma levels and vice versa[2]).
A recent focus has been on the role of thymulin as an effector on proinflammatory mediators/cytokines. A peptide analog of thymulin (PAT) has been found to have analgesic effects in higher concentrations and particularly neuroprotective anti-inflammatory effects in the CNS.[3] Astrocytes seem to be the target for thymulin for this effect. Researchers hope to develop drugs thwarting inflammatory processes associated with neurodegenerative diseases and even rheumatism with the help of thymulin analogs. Moreover, thymulin has been associated with anorexia nervosa.[4]
A recent focus has been on the role of thymulin as an effector on proinflammatory mediators/cytokines. A peptide analog of thymulin (PAT) has been found to have analgesic effects in higher concentrations and particularly neuroprotective anti-inflammatory effects in the CNS.[3] Astrocytes seem to be the target for thymulin for this effect. Researchers hope to develop drugs thwarting inflammatory processes associated with neurodegenerative diseases and even rheumatism with the help of thymulin analogs. Moreover, thymulin has been associated with anorexia nervosa.[4]
Product Categories/Family for Thymic Factor steroid
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Product Notes
The Thymic Factor (Catalog #AAA638974) is a Steroid produced from Synthetic peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Thymic Factor, Steroid" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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