Acid Sensing Ion Channels 4 Peptide | ASIC4 peptide

Acid Sensing Ion Channels 4, Human (ASIC4) Control Peptide

Cat. Num. AAA659897

• Gene Names: ASIC4; ACCN4; BNAC4
• Applications: ELISA
• Purity: Highly Purified; Highly purified
• Synonyms: Acid Sensing Ion Channels 4; Human (ASIC4) Control Peptide; ASIC4 peptide

• Host: Synthetic peptide (human)
• Purity/Purification: Highly Purified; Highly purified
• Form/Format: Supplied as a liquid in PBS, pH 7.5, 0.05% sodium azide.

• Applicable Applications for ASIC4 peptide: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA and Antibody Blocking. Not suitable for use in Western Blot.; Dilution: ELISA: Coat ELISA plates at 1ug/ml; Dilute antibody as instructed.; Antibody Blocking: 5-10ug per 1ul A0577 (antiserum) or 1ug A0577-05 (affinity purified antibody).
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for ASIC4 peptide

Control Peptide for A0577 (antiserum) and A0577-05 (affinity purified antibody).

Product Categories/Family for ASIC4 peptide

Molecular Biology; MB-Ion Channel

NCBI and Uniprot Product Information

• NCBI GI #: 256773230
• NCBI GeneID: 55515
• NCBI Accession #: NP_878267.2
• NCBI GenBank Nucleotide #: NM_182847.2
• UniProt Accession #: Q96FT7; Q53SB7; Q6GMS1; Q6PIN9; Q9NQA4
• Molecular Weight: 70,105 Da
• NCBI Official Full Name: acid-sensing ion channel 4
• NCBI Official Synonym Full Names: acid-sensing (proton-gated) ion channel family member 4
• NCBI Official Symbol: ASIC4
• NCBI Official Synonym Symbols: ACCN4; BNAC4
• NCBI Protein Information: acid-sensing ion channel 4; brain sodium channel 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary
• UniProt Protein Name: Acid-sensing ion channel 4
• Protein Family: Acid-sensing ion channel
• UniProt Gene Name: ASIC4
• UniProt Synonym Gene Names: ACCN4; ASIC4
• UniProt Entry Name: ASIC4_HUMAN

NCBI Description

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]

Uniprot Description

Function: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Ref.1

Subunit structure: Homotrimer or heterotrimer with other ASIC proteins

By similarity.

Subcellular location: Membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. Ref.1

Sequence similarities: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily. [View classification]

Sequence caution: The sequence CAB93980.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAC51338.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.