SLC26A6 sirna

SLC26A6 siRNA (Mouse)

Cat. Num. AAA8236371

• Gene Names: Slc26a6; CFEX; Pat1; Pat-1; B930010B04Rik
• Reactivity: Mouse
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: SLC26A6; SLC26A6 siRNA (Mouse); CFEX; PAT1; Solute carrier family 26 member 6; Anion exchange transporter; Chloride-formate exchanger; Pendrin-L1; Pendrin-like protein 1; Putative anion transporter-1; Pat-1; SLC26A6 sirna

• Host: Synthetic
• Reactivity: Mouse
• Specificity: SLC26A6 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 726

• Applicable Applications for SLC26A6 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse SLC26A6 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for SLC26A6 sirna

siRNA to inhibit SLC26A6 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 31981655
• NCBI GeneID: 171429
• NCBI Accession #: NP_599252.2
• NCBI GenBank Nucleotide #: NM_134420.4
• UniProt Accession #: Q8CIW6; Q3TQD3; Q812E2; Q8CJD0; Q8K142; Q923J3; E9Q4D3
• Molecular Weight: 79,108 Da
• NCBI Official Full Name: solute carrier family 26 member 6
• NCBI Official Synonym Full Names: solute carrier family 26, member 6
• NCBI Official Symbol: Slc26a6
• NCBI Official Synonym Symbols: CFEX; Pat1; Pat-1; B930010B04Rik
• NCBI Protein Information: solute carrier family 26 member 6
• UniProt Protein Name: Solute carrier family 26 member 6
• Protein Family: Solute carrier family
• UniProt Gene Name: Slc26a6
• UniProt Synonym Gene Names: Pat-1
• UniProt Entry Name: S26A6_MOUSE

Uniprot Description

SLC26A6: Does not seem to be involved in anion transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; brush border membrane; integral to plasma membrane; basolateral plasma membrane; cell; integral to membrane; vesicle membrane; membrane; apical plasma membrane; plasma membrane; cytoplasmic vesicle; intracellular

Molecular Function: formate transmembrane transporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; formate efflux transmembrane transporter activity; anion:anion antiporter activity; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; antiporter activity; PDZ domain binding; formate uptake transmembrane transporter activity; protein binding; efflux transmembrane transporter activity; chloride transmembrane transporter activity; sulfate transmembrane transporter activity; anion transmembrane transporter activity

Biological Process: intracellular pH elevation; epithelial fluid transport; transepithelial chloride transport; mannitol transport; sulfate transport; chloride transport; oxalic acid secretion; anion transport; intestinal absorption; transport; bicarbonate transport; regulation of intracellular pH; ion transport; oxalate transport; transmembrane transport; formate transport; sperm capacitation