AOX1 sirna
AOX1 siRNA (Mouse)
Gene Names
Aox1; Ao; Ro; Aox2; Moro; Aox-1; Aox-2; AI196512; AI255253
Reactivity
Mouse
Applications
RNA Interference (RNAi)
Purity
> 97%
Synonyms
AOX1; AOX1 siRNA (Mouse); AO; RO; Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; Retinal oxidase; AOX1 sirna
Host
Synthetic
Reactivity
Mouse
Specificity
AOX1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Sequence Length
1333
Applicable Applications for AOX1 sirna
RNA Interference (RNAi)
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse AOX1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for AOX1 sirna
siRNA to inhibit AOX1 expression using RNA interference
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
146,678 Da
NCBI Official Full Name
aldehyde oxidase 1
NCBI Official Synonym Full Names
aldehyde oxidase 1
NCBI Official Symbol
Aox1
NCBI Official Synonym Symbols
Ao; Ro; Aox2; Moro; Aox-1; Aox-2; AI196512; AI255253
NCBI Protein Information
aldehyde oxidase 1
UniProt Protein Name
Aldehyde oxidase 1
Protein Family
UniProt Gene Name
Aox1
UniProt Synonym Gene Names
Ao; Ro
UniProt Entry Name
AOXA_MOUSE
Uniprot Description
AOX1: Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]
Protein type: EC 1.2.3.1; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - vitamin B6; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Amino Acid Metabolism - tryptophan; Oxidoreductase
Cellular Component: cytoplasm
Molecular Function: molybdopterin cofactor binding; 2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; electron carrier activity; FAD binding; iron ion binding; metal ion binding; aldehyde oxidase activity; iron-sulfur cluster binding; oxidoreductase activity; NAD binding; catalytic activity; oxidoreductase activity, acting on CH-OH group of donors
Research Articles on AOX1
Similar Products
Product Notes
The AOX1 aox1 (Catalog #AAA8221869) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The AOX1 siRNA (Mouse) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AOX1 can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the AOX1 aox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AOX1, siRNA" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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