KIAA1109 sirna

KIAA1109 siRNA (Human)

Cat. Num. AAA829833

• Gene Names: KIAA1109; FSA; Tweek
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: KIAA1109; KIAA1109 siRNA (Human); FSA; KIAA1371; Uncharacterized protein KIAA1109; Fragile site-associated protein; KIAA1109 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: KIAA1109 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 5005

• Applicable Applications for KIAA1109 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human KIAA1109 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for KIAA1109 sirna

siRNA to inhibit KIAA1109 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 150378498
• NCBI GeneID: 84162
• NCBI Accession #: NP_056127.2
• NCBI GenBank Nucleotide #: NM_015312.3
• UniProt Accession #: Q2LD37; Q4W598; Q5CZA9; Q6ZS70; Q6ZV75; Q86XA5; Q8WVD8; Q9H742; Q9NT48; Q9NTC3; Q9NTI4; Q9P2H6
• Molecular Weight: 470,929 Da
• NCBI Official Full Name: uncharacterized protein KIAA1109
• NCBI Official Synonym Full Names: KIAA1109
• NCBI Official Symbol: KIAA1109
• NCBI Official Synonym Symbols: FSA; Tweek
• NCBI Protein Information: uncharacterized protein KIAA1109
• UniProt Protein Name: Uncharacterized protein KIAA1109
• UniProt Gene Name: KIAA1109
• UniProt Synonym Gene Names: FSA; KIAA1371
• UniProt Entry Name: K1109_HUMAN

NCBI Description

This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Uniprot Description

KIAA1109: This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q27

Cellular Component: membrane; integral to membrane; nucleus

Molecular Function: protein binding

Biological Process: regulation of epithelial cell differentiation; regulation of cell growth