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COX8A blocking peptide

COX8A Blocking Peptide

Gene Names
COX8A; COX; COX8; VIII; COX8L; COX8-2; VIII-L
Reactivity
Human, Mouse, Rat
Applications
Blocking (BL)
Purity
>85%
Synonyms
COX8A; COX8A Blocking Peptide; COX8; COX8L; Cytochrome c oxidase subunit 8A; mitochondrial; Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2; COX8A blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
69
Applicable Applications for COX8A blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for COX8A blocking peptide
The peptide is used to block Anti-COX8A Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,579 Da
NCBI Official Full Name
cytochrome c oxidase subunit 8A, mitochondrial
NCBI Official Synonym Full Names
cytochrome c oxidase subunit VIIIA (ubiquitous)
NCBI Official Symbol
COX8A
NCBI Official Synonym Symbols
COX; COX8; VIII; COX8L; COX8-2; VIII-L
NCBI Protein Information
cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit 8A (ubiquitous); cytochrome c oxidase polypeptide VIII-liver/heart
UniProt Protein Name
Cytochrome c oxidase subunit 8A, mitochondrial
UniProt Gene Name
COX8A
UniProt Synonym Gene Names
COX8; COX8L
UniProt Entry Name
COX8A_HUMAN

NCBI Description

The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]

Uniprot Description

COX8A: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIII family.

Protein type: Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Mitochondrial

Chromosomal Location of Human Ortholog: 11q12-q13

Cellular Component: mitochondrial inner membrane; integral to membrane

Molecular Function: cytochrome-c oxidase activity

Biological Process: cellular metabolic process; generation of precursor metabolites and energy; transmembrane transport

Research Articles on COX8A

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Product Notes

The COX8A cox8a (Catalog #AAA822895) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The COX8A Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's COX8A can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the COX8A cox8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COX8A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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