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Cytochrome P450 2U1 Blocking Peptide | CYP2U1 blocking peptide

Cytochrome P450 2U1 Blocking Peptide

Gene Names
CYP2U1; SPG49; SPG56; P450TEC
Reactivity
Human, Monkey
Applications
Blocking (BL)
Purity
>85%
Synonyms
Cytochrome P450 2U1; Cytochrome P450 2U1 Blocking Peptide; CYP2U1 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Monkey
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
544
Applicable Applications for CYP2U1 blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for CYP2U1 blocking peptide
The peptide is used to block Anti-Cytochrome P450 2U1 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,578 Da
NCBI Official Full Name
cytochrome P450 2U1
NCBI Official Synonym Full Names
cytochrome P450, family 2, subfamily U, polypeptide 1
NCBI Official Symbol
CYP2U1
NCBI Official Synonym Symbols
SPG49; SPG56; P450TEC
NCBI Protein Information
cytochrome P450 2U1; spastic paraplegia 49
UniProt Protein Name
Cytochrome P450 2U1
Protein Family
UniProt Gene Name
CYP2U1
UniProt Entry Name
CP2U1_HUMAN

NCBI Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]

Uniprot Description

CYP2U1: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Lipid Metabolism - arachidonic acid; Oxidoreductase; Membrane protein, multi-pass; EC 1.14.14.1

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm; integral to membrane

Molecular Function: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; steroid hydroxylase activity; oxygen binding

Biological Process: organic acid metabolic process; xenobiotic metabolic process; exogenous drug catabolic process; arachidonic acid metabolic process

Disease: Spastic Paraplegia 56, Autosomal Recessive

Research Articles on CYP2U1

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Product Notes

The CYP2U1 cyp2u1 (Catalog #AAA823137) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 2U1 Blocking Peptide reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 2U1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the CYP2U1 cyp2u1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 2U1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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