NFIA blocking peptide

NFIA Blocking Peptide

Cat. Num. AAA8202218

• Gene Names: NFIA; CTF; NF1-A; NFI-A; NFI-L; NF-I/A
• Reactivity: Human, Mouse, Rat, Bovine, Chicken, Porcine, Zebrafish
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: NFIA; NFIA Blocking Peptide; KIAA1439; Nuclear factor 1 A-type; NF1-A; Nuclear factor 1/A; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein; NFIB; Nuclear factor 1 B-type; NF1-B; Nuclear factor 1/B; Nuclear factor I/B; NF-I/B; NFI-B; NFIC; NFI; Nuclear factor 1 C-type; NF1-C; Nuclear factor 1/C; Nuclear factor I/C; NF-I/C; NFI-C; NFIX; Nuclear factor 1 X-type; NF1-X; Nuclear factor 1/X; Nuclear factor I/X; NF-I/X; NFI-X; NFIA blocking peptide

• Host: Synthetic
• Reactivity: Human, Mouse, Rat, Bovine, Chicken, Porcine, Zebrafish
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 509

• Applicable Applications for NFIA blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for NFIA blocking peptide

The peptide is used to block Anti-NFIA Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 197927284
• NCBI GeneID: 4774
• NCBI Accession #: NP_001128145.1
• NCBI GenBank Nucleotide #: NM_001134673.3
• UniProt Accession #: Q12857; Q8TA97; Q9H3X9; Q9P2A9; B4DRJ3; B4DS53; F5H0R0; F8W8W3
• Molecular Weight: 60,894 Da
• NCBI Official Full Name: nuclear factor 1 A-type isoform 1
• NCBI Official Synonym Full Names: nuclear factor I/A
• NCBI Official Symbol: NFIA
• NCBI Official Synonym Symbols: CTF; NF1-A; NFI-A; NFI-L; NF-I/A
• NCBI Protein Information: nuclear factor 1 A-type
• UniProt Protein Name: Nuclear factor 1 A-type
• Protein Family: Nuclear factor
• UniProt Gene Name: NFIA
• UniProt Synonym Gene Names: KIAA1439; NF1-A; Nuclear factor 1/A; CTF; NF-I/A; NFI-A
• UniProt Entry Name: NFIA_HUMAN

NCBI Description

This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

NFI-A: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1p31.3-p31.2

Cellular Component: nucleoplasm; cell junction; nucleus

Molecular Function: transcription factor activity; transcription factor binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; viral genome replication; DNA replication; response to organic cyclic substance