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Structure (Structure of L2051-35)

Levofloxacin Hemihydrate Biochemical

Levofloxacin Hemihydrate ((-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, Hemihydrate)

Purity
0.98
Synonyms
Levofloxacin Hemihydrate; Levofloxacin Hemihydrate ((-)-(S)-9-Fluoro-2; 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1; 2; 3-de]-1; 4-benzoxazine-6-carboxylic Acid; Hemihydrate); Levofloxacin Hemihydrate biochemical
Ordering
For Research Use Only!
Host
Synthetic
Purity/Purification
0.98
Form/Format
Supplied as a pale yellow solid
Melting Point:
214-216ºC
CAS Number
100986-85-4
Molecular Formula
C18H20FN3O4• 01/2H2O
Method for Determining Identity
1H NMR Spectroscopic Analysis
Solubility
Methanol
TLC Conditions
SiO2; Dichloromethane: Methanol: NH4OH; 5:5:1; Visualized with UV and AMCS; Single spot; Rf=0.5. 1H NMR conforms to structure.
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Structure

(Structure of L2051-35)

Structure (Structure of L2051-35)
Related Product Information for Levofloxacin Hemihydrate biochemical
Levofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class[1][2] and is used to treat severe or life-threatening bacterial infections or bacterial infections that have failed to respond to other antibiotic classes.[3][4] It is sold under various brand names, such as Levaquin and Tavanic, the most common. In form of ophthalmic solutions it is known as Oftaquix, Quixin and Iquix.

Levofloxacin is a chiral fluorinated carboxyquinolone. Investigation of ofloxacin, an older drug that is the racemic mixture, found that the l form [the (-)-(S) enantiomer] is more active. This specific component is levofloxacin.[5][6]
Levofloxacin interacts with a number of other drugs, as well as a number of herbal and natural supplements. Such interactions increase the risk of cardiotoxicity and arrhythmias, anticoagulation, the formation of non-absorbable complexes, as well as increasing the risk of toxicity.[7]
Levofloxacin is associated with a number of serious and life-threatening adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Such reactions may manifest long after therapy had been completed and in severe cases may result in life-long disabilities. Hepatoxicity has also been reported with the use of levofloxacin.[8][9]
Product Categories/Family for Levofloxacin Hemihydrate biochemical

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Product Notes

The Levofloxacin Hemihydrate (Catalog #AAA6074883) is a Biochemical produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Levofloxacin Hemihydrate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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