Histone-lysine N-methyltransferase SUV39H2 (suv39h2) Recombinant Protein | suv39h2 recombinant protein
Recombinant Xenopus tropicalis Histone-lysine N-methyltransferase SUV39H2 (suv39h2)
NCBI and Uniprot Product Information
Uniprot Description
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes ().
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Product Notes
The suv39h2 suv39h2 (Catalog #AAA1468055) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-406, Full length protein. The amino acid sequence is listed below: MAAARGAWCV PCLASIETLQ ELCRKEMLIC TNIGITRKNL NNYEVEYLCD YRIEKGVEKF FVKWKGWPES CNTWEPTRNL KCPTLLKQFY SDLYNYFCAL KPNKKGFLKN SIKSLDPSLS DYIVKKAKQR IALRRWEEEL NRKKTHSGTL FVENTVDLEG PPMDFYYIND YKASPGVNTL GEAIVGCDCS DCFKGKCCPT EAGVLFAYNE HRQIKIPPGR PIYECNSRCK CGPDCPNRVV QKGPPYSLCI FRTDNGRGWG VKTLQKIKKN SFVMEYVGEV ITSEEAERRG QQYDSRGITY LFDLDYEADE FTVDAARYGN VSHFVNHSCD PNLQVFNVFI DNLDVRLPRI ALFSTRNIKA GEELTFDYQM KGSGDFSTDS IDMSPAKKRV RIACKCGAAT CRGYLN. It is sometimes possible for the material contained within the vial of "Histone-lysine N-methyltransferase SUV39H2 (suv39h2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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