Human sulfotransferase family, cytosolic, 2B, member 1 ELISA Kit | SULT2B1 elisa kit
Human Sulfotransferase family cytosolic 2B member 1, SULT2B1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
SULT2B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - androgen and estrogen; Energy Metabolism - sulfur; Transferase; EC 2.8.2.2
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; cytosol; nucleus
Molecular Function: protein binding; alcohol sulfotransferase activity; steroid sulfotransferase activity
Biological Process: steroid metabolic process; sulfate assimilation; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Research Articles on SULT2B1
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Product Notes
The Human SULT2B1 sult2b1 (Catalog #AAA9319648) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319648 ELISA Kit recognizes Human SULT2B1. It is sometimes possible for the material contained within the vial of "sulfotransferase family, cytosolic, 2B, member 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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