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Sulfotransferase Family Recombinant Protein | SULT1C4 recombinant protein

Recombinant Human Sulfotransferase Family, Cytosolic 1C, Member 4

Gene Names
SULT1C4; SULT1C; SULT1C2
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Sulfotransferase Family; Recombinant Human Sulfotransferase Family; Cytosolic 1C; Member 4; SULT1C4 Human; Member 4 Human Recombinant; Sulfotransferase 1C4; SULT1C; SULT1C2; SULT1C4; ST1C4; Sulfotransferase 1C2; SULT1C#2; SULT1C4 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
SULT1C4 protein solution (1mg/ml) containing 0.1M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MALHDMEDFT FDGTKRLSVN YVKGILQPTD TCDIWDKIWN FQAKPDDLLI STYPKAGTTW TQEIVELIQN EGDVEKSKRA PTHQRFPFLE MKIPSLGSGL EQAHAMPSPR ILKTHLPFHL LPPSLLEKNC KIIYVARNPK DNMVSYYHFQ RMNKALPAPG TWEEYFETFL AGKVCWGSWH EHVKGWWEAK DKHRILYLFY EDMKKNPKHE IQKLAEFIGK KLDDKVLDKI VHYTSFDVMK QNPMANYSSI PAEIMDHSIS PFMRKGAVGD WKKHFTVAQN ERFDEDYKKK MTDTRLTFHF QF.
Sequence Length
302
Related Product Information for SULT1C4 recombinant protein
Description: SULT1C4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-302 a.a) and having a molecular mass of 37.6kDa. SULT1C4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Sulfotransferase 1C4 (SULT1C4) is a member of the SULT subfamily. SULT1C4 is responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. Sulfotransferase enzymes are different in their tissue distributions and substrate specificities. SULT1C4 catalyzes the sulfonation of p-nitrophenol and N-hydroxy-2-acetylaminofluorene, except dopamine.
Product Categories/Family for SULT1C4 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,841 Da
NCBI Official Full Name
sulfotransferase 1C4
NCBI Official Synonym Full Names
sulfotransferase family, cytosolic, 1C, member 4
NCBI Official Symbol
SULT1C4
NCBI Official Synonym Symbols
SULT1C; SULT1C2
NCBI Protein Information
sulfotransferase 1C4; ST1C4; SULT1C#2; sulfotransferase 1C2; sulfotransferase family, cytosolic, 1C, member 2; sulfotransferase family, cytosolic, 1C, member C2
UniProt Protein Name
Sulfotransferase 1C4
Protein Family
UniProt Gene Name
SULT1C4
UniProt Synonym Gene Names
SULT1C2; ST1C4; SULT1C#2
UniProt Entry Name
ST1C4_HUMAN

NCBI Description

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008]

Uniprot Description

SULT1C4: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Belongs to the sulfotransferase 1 family.

Protein type: EC 2.8.2.-; Transferase

Chromosomal Location of Human Ortholog: 2q12.3

Cellular Component: cytosol

Molecular Function: sulfotransferase activity

Biological Process: xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process

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Product Notes

The SULT1C4 sult1c4 (Catalog #AAA146369) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MALHDMEDFT FDGTKRLSVN YVKGILQPTD TCDIWDKIWN FQAKPDDLLI STYPKAGTTW TQEIVELIQN EGDVEKSKRA PTHQRFPFLE MKIPSLGSGL EQAHAMPSPR ILKTHLPFHL LPPSLLEKNC KIIYVARNPK DNMVSYYHFQ RMNKALPAPG TWEEYFETFL AGKVCWGSWH EHVKGWWEAK DKHRILYLFY EDMKKNPKHE IQKLAEFIGK KLDDKVLDKI VHYTSFDVMK QNPMANYSSI PAEIMDHSIS PFMRKGAVGD WKKHFTVAQN ERFDEDYKKK MTDTRLTFHF QF.. It is sometimes possible for the material contained within the vial of "Sulfotransferase Family, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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