Structure
(Structure of C7852-20.)
Concanamycin A Antibiotic
Concanamycin A (Folimycin, Antibiotic TAN 1323B)
Purity
Highly Purified>99% by HPLC
Synonyms
Concanamycin A; Concanamycin A (Folimycin; Antibiotic TAN 1323B); Concanamycin A antibiotic
Host
Streptomyces sp.
Purity/Purification
Highly Purified
>99% by HPLC
>99% by HPLC
Form/Format
Supplied as a lyophilized powder.
CAS Number
80890-47-7
Molecular Formula
C46H75NO14
Solubility
Soluble in ethanol, methanol, DMF or DMSO
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Structure
(Structure of C7852-20.)
Structure
(Structure of C7852-20.)
Related Product Information for Concanamycin A antibiotic
Concanamycin A is the major analogue of the concanamycin complex produced by Streptomyces sp. It has has been shown to act as a potent and specific vacuolar-APTase inhibitor. Concanamycin A inhibits the acidification of organelles and blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. It also interferes with intracellular protein trafficking and inhibits perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity. Concanamycins are structurally related to the bafilomycins.
Product Categories/Family for Concanamycin A antibiotic
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Concanamycin A (Catalog #AAA651273) is an Antibiotic produced from Streptomyces sp. and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Concanamycin A, Antibiotic" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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