Mouse serine/threonine kinase 36, fused homolog (Drosophila) ELISA Kit | STK36 elisa kit
Mouse Serine/threonine-protein kinase 36, STK36 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Fused: a serine/threonine protein kinase of the ULK family. Plays a role in Hedgehog (Hh) signaling. Interacts with Smoothened (Smo), the receptor for Hedgehog (Hh). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of Fused to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Two alternatively spliced isoforms have been described.
Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Other group; ULK family
Cellular Component: cytoplasm; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; transcription factor binding; ATP binding; protein kinase activity
Biological Process: cell projection organization and biogenesis; regulation of transcription factor activity; multicellular organismal development; positive regulation of smoothened signaling pathway; cilium biogenesis; brain development; protein amino acid phosphorylation; phosphorylation; activation of hh target transcription factor; post-embryonic development
Research Articles on STK36
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Product Notes
The Mouse STK36 stk36 (Catalog #AAA9317995) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317995 ELISA Kit recognizes Mouse STK36. It is sometimes possible for the material contained within the vial of "serine/threonine kinase 36, fused homolog (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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