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Typical Testing Data/Standard Curve (for reference only) (The LumiAb, Human Osteopontin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Osteopontin proteins within the range of 15-1000 pg/ml.)

Human Osteopontin CLIA Kit | SPP1 clia kit

Osteopontin (Human) LumiAb ELISA Kit

Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Reactivity
Human
Synonyms
Osteopontin; Osteopontin (Human) LumiAb ELISA Kit; Human Osteopontin; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin; SPP1 clia kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
The LumiAb, Human Osteopontin ELISA is capable of recognizing both recombinant and naturally produced Human Osteopontin proteins.
The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: MMP-3
Sequence Length
300
Assay Type
Sandwich ELISA
Detection Range
15-1000 pg/ml
Detection Method
Luminometer
Sub Type
None
Preparation and Storage
Store at 4 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

(The LumiAb, Human Osteopontin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Osteopontin proteins within the range of 15-1000 pg/ml.)

Typical Testing Data/Standard Curve (for reference only) (The LumiAb, Human Osteopontin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Osteopontin proteins within the range of 15-1000 pg/ml.)
Product Categories/Family for SPP1 clia kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
osteopontin isoform OPN-b
NCBI Official Synonym Full Names
secreted phosphoprotein 1
NCBI Official Symbol
SPP1
NCBI Official Synonym Symbols
OPN; BNSP; BSPI; ETA-1
NCBI Protein Information
osteopontin
UniProt Protein Name
Osteopontin
Protein Family
UniProt Gene Name
SPP1
UniProt Synonym Gene Names
BNSP; OPN; SPP-1
UniProt Entry Name
OSTP_HUMAN

NCBI Description

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

osteopontin: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Belongs to the osteopontin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: extracellular space; cell projection; perinuclear region of cytoplasm; apical part of cell; extracellular region

Molecular Function: protein binding; extracellular matrix binding; cytokine activity

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; decidualization; osteoblast differentiation; extracellular matrix disassembly; response to vitamin D; biomineral formation; response to steroid hormone stimulus; negative regulation of collateral sprouting of intact axon in response to injury; positive regulation of bone resorption; inflammatory response; cell adhesion; embryo implantation

Research Articles on SPP1

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Product Notes

The Human SPP1 spp1 (Catalog #AAA9510993) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9510993 CLIA Kit recognizes Human SPP1. It is sometimes possible for the material contained within the vial of "Osteopontin, CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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