Probable ATP-dependent RNA helicase spindle-E (spn-E) Recombinant Protein | spn-E recombinant protein

Recombinant Drosophila ananassae Probable ATP-dependent RNA helicase spindle-E (spn-E), partial

• Gene Names: DanaGF18547; dana_GLEANR_19803; GF18547
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable ATP-dependent RNA helicase spindle-E (spn-E); Recombinant Drosophila ananassae Probable ATP-dependent RNA helicase spindle-E (spn-E); partial; spn-E recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,429

• Species: Drosophila ananassae (Fruit fly)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 964152129
• NCBI GeneID: 6501320
• NCBI Accession #: XP_001954983.2
• NCBI GenBank Nucleotide #: XM_001954947.2
• UniProt Accession #: B3M383
• Molecular Weight: 164,179 Da
• NCBI Official Full Name: uncharacterized protein Dana_GF18547
• NCBI Official Symbol: DanaGF18547
• NCBI Official Synonym Symbols: dana_GLEANR_19803; GF18547
• NCBI Protein Information: GF18547 gene product from transcript GF18547-RA
• UniProt Protein Name: Probable ATP-dependent RNA helicase spindle-E
• Protein Family: Probable ATP-dependent RNA helicase
• UniProt Gene Name: spn-E
• UniProt Synonym Gene Names: hls

Uniprot Description

Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements. Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin. Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats. Required for anteroposterior and dorsoventral axis formation during oogenesis ().