Sperm Equatorial Segment Protein 1/SPESP1 Recombinant Protein | SPESP1 recombinant protein
Recombinant Human Sperm Equatorial Segment Protein 1/SPESP1 Protein (C-6His)
Gene Names
SPESP1; ESP; SP-ESP
Purity
>90% as determined by reducing SDS-PAGE.
Synonyms
Sperm Equatorial Segment Protein 1/SPESP1; Recombinant Human Sperm Equatorial Segment Protein 1/SPESP1 Protein (C-6His); Sperm Equatorial Segment Protein 1; ESP; Equatorial Segment Protein; SP-ESP; Glycosylated 38 kDa Sperm Protein C-7/8; SPESP1; SPESP1 recombinant protein
Host
Human Cells
Purity/Purification
>90% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence Positions
Tyr20-Tyr350
Sequence Length
350
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for SPESP1 recombinant protein
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 37.9 kDa
Actual Protein Molecular Mass: 58 kDa
Actual Protein Molecular Mass: 58 kDa
NCBI Official Full Name
sperm equatorial segment protein 1
NCBI Official Synonym Full Names
sperm equatorial segment protein 1
NCBI Official Symbol
SPESP1
NCBI Official Synonym Symbols
ESP; SP-ESP
NCBI Protein Information
sperm equatorial segment protein 1
UniProt Protein Name
Sperm equatorial segment protein 1
Protein Family
UniProt Gene Name
SPESP1
UniProt Synonym Gene Names
ESP1 PublicationManual assertion based on opinion iniRef.1
NCBI Description
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]
Uniprot Description
Involved in fertilization ability of sperm.
Research Articles on SPESP1
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Product Notes
The SPESP1 spesp1 (Catalog #AAA2553250) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Tyr20-Tyr350. It is sometimes possible for the material contained within the vial of "Sperm Equatorial Segment Protein 1/SPESP1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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